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- Title
Effect of nucleocapsid on multimerization of gypsy structural protein GAG.
- Authors
Syomin, B.; Leonova, O.; Trendeleva, T.; Zvyagilskaya, R.; Ilyin, Yu.; Popenko, V.
- Abstract
The structural protein (Gag) of Drosophila retrovirus gypsy contains capsid and nucleocapsid domains. Gag forms virus-like particles in a bacterial cell; furthermore, its capsid alone is able to form aggregates. However, aggregates assembled from the capsid vary in size and are less organized than particles formed by a full-length Gag. The nucleocapsid determines the organization and structure of the particles, which is ensured by the amino acid residues at its N-terminal (a nucleocapsid proximal part). The assembly of the particle occurs in the presence of any RNAs or single-stranded DNA oligonucleotides.
- Subjects
NUCLEOCAPSIDS; CYTOSKELETAL proteins; DROSOPHILA; RETROVIRUSES; CAPSIDS; BACTERIAL cells; RETROTRANSPOSONS; GAG proteins
- Publication
Molecular Biology, 2012, Vol 46, Issue 2, p270
- ISSN
0026-8933
- Publication type
Article
- DOI
10.1134/S0026893312020148