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- Title
Influence of parental history of hypertension on blood pressure.
- Authors
Lascaux-Lefebvre, V; Ruidavets, J B; Arveiler, D; Amouyel, P; Haas, B; Cottel, D; Bingham, A; Ducimetière, P; Ferrières, J
- Abstract
Aim: To assess the effect of parental history of hypertension on blood pressure in representative samples from three French populations (MONICA centres of Lille, Strasbourg, Toulouse). Methods: We screened 1660 males and 1635 females, aged 35-64 years. Subjects were defined as hypertensive if systolic blood pressure ⩾160 mm Hg or diastolic blood pressure ⩾95 mm Hg or if they were treated by antihypertensive drugs. Four groups of parental history were determined: no parental history; at least one parent hypertensive before 60 years; hypertension was diagnosed after 60; and hypertension with unknown age of discovery. A logistic regression model was used separately for each sex. Results: After adjustment for age, body mass index, physical exercise, educational level, tobacco consumption, alcohol consumption, high density lipoprotein cholesterol, centre, diabetes mellitus and hypercholes-terolaemia, parental history before age 60 was related to offspring's hypertension: OR = 2.09 (95% CI: 1.42-3.09) in men, and OR = 2.77 (95% CI: 1.95-3.93) in women. This relationship was stronger when we compared two parental histories versus none (women: OR = 5.33, 95% CI: 1.30-21.94; men: OR = 7.78, 95% CI: 2.45-24.74). Conclusion: In this representative cross-sectional study, history of hypertension in at least one parent was associated with offspring's hypertension.
- Subjects
HYPERTENSION; BLOOD pressure; EPIDEMIOLOGY; GENEALOGY
- Publication
Journal of Human Hypertension, 1999, Vol 13, Issue 9, p631
- ISSN
0950-9240
- Publication type
Article
- DOI
10.1038/sj.jhh.1000884