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Cell cycle and cancer.
Published in:
1995
By:
- Clurman, Bruce E.;
- Roberts, James M.
Publication type:
Editorial
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22319-5
By:
- Khan, Omar M.;
- Almagro, Jorge;
- Nelson, Jessica K.;
- Horswell, Stuart;
- Encheva, Vesela;
- Keyan, Kripa S.;
- Clurman, Bruce E.;
- Snijders, Ambrosius P.;
- Behrens, Axel
Publication type:
Article
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1 , is disrupted in osteosarcoma.
Published in:
Journal of Cell Biology, 2004, v. 167, n. 5, p. 925, doi. 10.1083/jcb.200409187
By:
- Thomas, David M.;
- Johnson, Sandra A.;
- Sims, Natalie A.;
- Trivelt, Melanie K.;
- Slavin, John L.;
- Rubin, Brian R.;
- Waring, Paul;
- Mcarthur, Grant A.;
- Walkley, Carl R.;
- Holloway, Andrew J.;
- Diyagama, Dileepa;
- Grim, Jonathon E.;
- Clurman, Bruce E.;
- Bowiell, David D.L.;
- Lee, Jong-Seo;
- Gutierrez, Gabriel M.;
- Piscopo, Denise M.;
- Carty, Shannon A.;
- Hinds, Philip W.
Publication type:
Article
Effect of Xpcl1 Activation and p27Kip1 Loss on Gene Expression in Murine Lymphoma.
Published in:
PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0014758
By:
- Kuppers, Daniel A.;
- Hwang, Harry C.;
- Jackson, Aimee L.;
- Linsley, Peter S.;
- Clurman, Bruce E.;
- Fero, Matthew L.
Publication type:
Article
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.74338
By:
- Thirmanne, H. Nayanga;
- Feinan Wu;
- Janssens, Derek H.;
- Swanger, Jherek;
- Diab, Ahmed;
- Feldman, Heather M.;
- Amezquita, Robert A.;
- Gottardo, Raphael;
- Paddison, Patrick J.;
- Henikoff, Steven;
- Clurman, Bruce E.
Publication type:
Article
Cyclin E in normal and neoplastic cell cycles.
Published in:
Oncogene, 2005, v. 24, n. 17, p. 2776, doi. 10.1038/sj.onc.1208613
By:
- Hwang, Harry C;
- Clurman, Bruce E
Publication type:
Article
Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP.
Published in:
PLoS Pathogens, 2019, v. 15, n. 1, p. 1, doi. 10.1371/journal.ppat.1007543
By:
- Dye, Kristine N.;
- Welcker, Markus;
- Clurman, Bruce E.;
- Roman, Ann;
- Galloway, Denise A.
Publication type:
Article
Fbw7/hCDC4 dimerization regulates its substrate interactions.
Published in:
Cell Division, 2007, v. 2, p. 7, doi. 10.1186/1747-1028-2-7
By:
- Welcker, Markus;
- Clurman, Bruce E.
Publication type:
Article
Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
Published in:
Journal of Cell Biology, 2008, v. 181, n. 6, p. 913, doi. 10.1083/jcb.200802076
By:
- Grim, Jonathan E.;
- Gustafson, Michael P.;
- Hirata, Roli K.;
- Hagar, Amanda C.;
- Swanger, Jherek;
- Welcker, Markus;
- Hwang, Harry C.;
- Ericsson, Johan;
- Russell, David W.;
- Clurman, Bruce E.
Publication type:
Article
Fbw7 Repression by Hes5 Creates a Feedback Loop That Modulates Notch-Mediated Intestinal and Neural Stem Cell Fate Decisions.
Published in:
PLoS Biology, 2013, v. 11, n. 6, p. 1, doi. 10.1371/journal.pbio.1001586
By:
- Sancho, Rocio;
- Blake, Sophia M.;
- Tendeng, Christian;
- Clurman, Bruce E.;
- Lewis, Julian;
- Behrens, Axel
Publication type:
Article
RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02497-x
By:
- Goyal, Nadish;
- Rossi, Matthew J.;
- Mazina, Olga M.;
- Mazin, Alexander V.;
- Clurman, Bruce E.;
- Chi, Yong;
- Moritz, Robert L.
Publication type:
Article
A Mechanism Misregulating p27 in Tumors Discovered in a Functional Genomic Screen.
Published in:
PLoS Genetics, 2007, v. 3, n. 12, p. e219, doi. 10.1371/journal.pgen.0030219
By:
- Garrett-Engele, Carrie M.;
- Tasch, Michael A.;
- Hwang, Harry C.;
- Fero, Matthew L.;
- Perlmutter, Roger M.;
- Clurman, Bruce E.;
- Roberts, James M.
Publication type:
Article
Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41805-x
By:
- Loeb, Keith R.;
- Hughes, Bridget T.;
- Fissel, Brian M.;
- Osteen, Nyka J.;
- Knoblaugh, Sue E.;
- Grim, Jonathan E.;
- Drury, Luke J.;
- Sarver, Aaron;
- Dupuy, Adam J.;
- Clurman, Bruce E.
Publication type:
Article
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation.
Published in:
2008
By:
- Welcker, Markus;
- Clurman, Bruce E.
Publication type:
journal article

Found: 14

Cell cycle and cancer.

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.

Terminal osteoblast differentiation, mediated by runx2 and p27<sup>KIP1</sup> , is disrupted in osteosarcoma.

Effect of Xpcl1 Activation and p27<sup>Kip1</sup> Loss on Gene Expression in Murine Lymphoma.

Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.

Cyclin E in normal and neoplastic cell cycles.

Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP.

Fbw7/hCDC4 dimerization regulates its substrate interactions.

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.

<i>Fbw7</i> Repression by Hes5 Creates a Feedback Loop That Modulates Notch-Mediated Intestinal and Neural Stem Cell Fate Decisions.

RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions.

A Mechanism Misregulating p27 in Tumors Discovered in a Functional Genomic Screen.

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation.