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- Title
Screening of toxoplasmosis in cancer patients: a concern.
- Authors
Abdoli, Amir; Barati, Mohammad; Pirestani, Majid; Dalimi, Abdolhossein
- Abstract
Toxoplasmosis is an opportunistic infectious disease in immunocompromised patients, including cancer patients, whose detection is by molecular and serological methods. A total of 106 blood samples from patients with different types of cancer were evaluated for anti- Toxoplasma gondii IgG and IgM antibodies by the enzyme-linked immunosorbent assay (ELISA) and the parasite DNA by nested polymerase chain reaction (PCR). These were detected in 41.51% (44/106) and 0.94% (1/106), respectively, but T. gondii IgM antibody was not detected at all. These results suggest that the screening of toxoplasmosis should be considered more routinely in cancer patients.
- Subjects
CANCER patients; DNA polymerases; BLOOD sampling; EARLY detection of cancer; IMMUNOCOMPROMISED patients; TOXOPLASMOSIS diagnosis; DNA analysis; ENZYME-linked immunosorbent assay; IMMUNOGLOBULINS; MEDICINE; POLYMERASE chain reaction; PROTOZOA; TOXOPLASMOSIS; TUMORS; DISEASE complications
- Publication
Tropical Doctor, 2019, Vol 49, Issue 1, p31
- ISSN
0049-4755
- Publication type
journal article
- DOI
10.1177/0049475518801618