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- Title
A TELOMERASE E A TERAPÊUTICA DO CANCRO: FUTURAS PERSPECTIVAS.
- Authors
Pedrosa, Nuno; Cardoso, Inês Lopes; Machado, Joana Queiroz
- Abstract
Telomeres are located at chromosomes ends, having essential roles in preventing terminal fusions. Several telomeric proteins were recently identified, however most of their functions are not yet understood. Mutations at the genes encoding these proteins cause a number of rare genetic syndromes, characterized by genetic and/or chromosome instability and predisposition to cancer. The understanding of the whole mechanism of operation of telomere biology, will enable the development of new methods of diagnosis, prevention and more effective treatment for each syndrome.
- Subjects
TELOMERES; CHROMOSOMES; GENETIC mutation; PROTEINS; DIAGNOSIS; CANCER risk factors
- Publication
Revista da Faculdade de Ciências da Saúde, 2008, Vol 5, p114
- ISSN
1646-0480
- Publication type
Article