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Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.
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- Current Osteoporosis Reports, 2017, v. 15, n. 3, p. 142, doi. 10.1007/s11914-017-0355-2
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- Article
Articular Cartilage: Structural and Developmental Intricacies and Questions.
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- Current Osteoporosis Reports, 2015, v. 13, n. 6, p. 407, doi. 10.1007/s11914-015-0290-z
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- Article
Polarizing Activity in Early Limb Cartilaginous Condensations.
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- Annals of the New York Academy of Sciences, 1996, v. 785, n. 1, p. 281, doi. 10.1111/j.1749-6632.1996.tb56284.x
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- Article
Hypertrophic Chondrocytes.
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- Annals of the New York Academy of Sciences, 1990, v. 599, n. 1, p. 45, doi. 10.1111/j.1749-6632.1990.tb42363.x
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- Article
Effect of a tumour promoter on myogenesis.
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- Nature, 1977, v. 266, n. 5602, p. 538, doi. 10.1038/266538a0
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- Article
Comment on ’Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity’.
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- eLife, 2019, p. 1, doi. 10.7554/eLife.43173.001
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- Article
Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization.
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- Microscopy Research & Technique, 1994, v. 28, n. 6, p. 483, doi. 10.1002/jemt.1070280604
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- Article
Retinoid Signaling Regulates CTGF Expression in Hypertrophic Chondrocytes With Differential Involvement of MAP Kinases.
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- Journal of Bone & Mineral Research, 2005, v. 20, n. 5, p. 867, doi. 10.1359/JBMR.041235
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Antiangiogenic Treatment Delays Chondrocyte Maturation and Bone Formation During Limb Skeletogenesis.
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- Journal of Bone & Mineral Research, 2002, v. 17, n. 1, p. 56, doi. 10.1359/jbmr.2002.17.1.56
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- Article
Activation of Transforming Growth Factor β in Chondrocytes Undergoing Endochondral Ossification.
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- Journal of Bone & Mineral Research, 2001, v. 16, n. 12, p. 2339, doi. 10.1359/jbmr.2001.16.12.2339
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- Article
Hedgehog Proteins Stimulate Chondrogenic Cell Differentiation and Cartilage Formation.
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- Journal of Bone & Mineral Research, 2000, v. 15, n. 9, p. 1659, doi. 10.1359/jbmr.2000.15.9.1659
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- Article
Transient Chondrogenic Phase in the Intramembranous Pathway During Normal Skeletal Development.
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- Journal of Bone & Mineral Research, 2000, v. 15, n. 3, p. 522, doi. 10.1359/jbmr.2000.15.3.522
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- Article
Articular Chondrocytes Produce Factors That Inhibit Maturation of Sternal Chondrocytes in Serum-Free Agarose Cultures: A TGF-β Independent Process.
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- Journal of Bone & Mineral Research, 1997, v. 12, n. 9, p. 1368, doi. 10.1359/jbmr.1997.12.9.1368
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Involvement of α5β1 Integrin in Matrix Interactions and Proliferation of Chondrocytes.
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- Journal of Bone & Mineral Research, 1997, v. 12, n. 7, p. 1124, doi. 10.1359/jbmr.1997.12.7.1124
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Retinoic acid induces a shift in the energetic state of hypertrophic chondrocytes.
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- Journal of Bone & Mineral Research, 1994, v. 9, n. 8, p. 1229, doi. 10.1002/jbmr.5650090813
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Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-? agonists.
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- Nature Medicine, 2012, v. 18, n. 10, p. 1592, doi. 10.1038/nm1012-1592b
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Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists.
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- Nature Medicine, 2011, v. 17, n. 4, p. 454, doi. 10.1038/nm.2334
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Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
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- PLoS Genetics, 2017, v. 13, n. 4, p. 1, doi. 10.1371/journal.pgen.1006742
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- Article
Hox11 paralogous genes are required for formation of wrist and ankle joints and articular surface organization.
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- Annals of the New York Academy of Sciences, 2010, v. 1192, n. 1, p. 307, doi. 10.1111/j.1749-6632.2009.05234.x
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- Article
Synovial Joint Formation during Mouse Limb Skeletogenesis.
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- Annals of the New York Academy of Sciences, 2007, v. 1116, p. 100, doi. 10.1196/annals.1402.063
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- Article
Chick limbs with mouse teeth: An effective in vivo culture system for tooth germ development and analysis.
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- Developmental Dynamics, 2003, v. 226, n. 1, p. 149, doi. 10.1002/dvdy.10217
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Expression, gene regulation, and roles of Fisp12/CTGF in developing tooth germs.
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- Developmental Dynamics, 2002, v. 224, n. 3, p. 267, doi. 10.1002/dvdy.10109
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Vascular regression is required for mesenchymal condensation and chondrogenesis in the developing limb.
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- Developmental Dynamics, 2001, v. 222, n. 3, p. 522, doi. 10.1002/dvdy.1212
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Development of stratum intermedium and its role as a Sonic hedgehog-signaling structure during odontogenesis.
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- Developmental Dynamics, 2001, v. 222, n. 2, p. 178, doi. 10.1002/dvdy.1186
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- Article
Early chick limb cartilaginous elements possess polarizing activity and express hedgehog-related morphogenetic factors.
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- Developmental Dynamics, 1996, v. 207, n. 3, p. 344, doi. 10.1002/(SICI)1097-0177(199611)207:3<344::AID-AJA11>3.0.CO;2-4
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- Article
Polarizing activity, Sonic hedgehog, and tooth development in embryonic and postnatal mouse.
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- Developmental Dynamics, 1996, v. 206, n. 1, p. 59, doi. 10.1002/(SICI)1097-0177(199605)206:1<59::AID-AJA6>3.0.CO;2-#
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- Article
Syndecan-3, tenascin-C, and the development of cartilaginous skeletal elements and joints in chick limbs.
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- Developmental Dynamics, 1995, v. 203, n. 2, p. 152, doi. 10.1002/aja.1002030204
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Tenascin is associated with articular cartilage development.
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- Developmental Dynamics, 1993, v. 198, n. 2, p. 123, doi. 10.1002/aja.1001980206
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- Article
Cellular and Molecular Mechanisms of Synovial Joint and Articular Cartilage Formation.
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- Annals of the New York Academy of Sciences, 2006, v. 1068, n. 1, p. 74, doi. 10.1196/annals.1346.010
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- Article
Regulating Mechanotransduction in Three Dimensions using Sub‐Cellular Scale, Crosslinkable Fibers of Controlled Diameter, Stiffness, and Alignment.
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- Advanced Functional Materials, 2019, v. 29, n. 18, p. N.PAG, doi. 10.1002/adfm.201808967
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- Article
Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.
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- Journal of Orthopaedic Research, 2022, v. 40, n. 10, p. 2391, doi. 10.1002/jor.25260
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Genetic and pharmacological inhibition of retinoic acid receptor γ function promotes endochondral bone formation.
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- Journal of Orthopaedic Research, 2017, v. 35, n. 5, p. 1096, doi. 10.1002/jor.23347
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- Article
Collagen Synthesis in Virus-transformed Cellsa.
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- Annals of the New York Academy of Sciences, 1985, v. 460, n. 1, p. 202, doi. 10.1111/j.1749-6632.1985.tb51168.x
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- Article
Activin A marks a novel progenitor cell population during fracture healing and reveals a therapeutic strategy.
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- eLife, 2024, p. 1, doi. 10.7554/eLife.89822
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Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop.
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- Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.732728
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Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B.
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- PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0229254
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Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function.
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- PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0222784
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- Article
SHP2 ablation mitigates osteoarthritic cartilage degeneration by promoting chondrocyte anabolism through SOX9.
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- FASEB Journal, 2024, v. 38, n. 17, p. 1, doi. 10.1096/fj.202400642R
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GRK2, a novel regulator of skeletal development.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.L7919
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- Article
Heparan sulfate in skeletal development, growth, and pathology: The case of hereditary multiple exostoses.
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- Developmental Dynamics, 2013, v. 242, n. 9, p. 1021, doi. 10.1002/dvdy.24010
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- Article
Shop talk: Sugars, bones, and a disease called multiple hereditary exostoses.
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- Developmental Dynamics, 2010, v. 239, n. 6, p. 1901, doi. 10.1002/dvdy.22290
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Temporomandibular joint formation and condyle growth require Indian hedgehog signaling.
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- Developmental Dynamics, 2007, v. 236, n. 2, p. 426, doi. 10.1002/dvdy.21036
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Expression and roles of connective tissue growth factor in Meckel's cartilage development.
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- Developmental Dynamics, 2004, v. 231, n. 1, p. 136
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Indian hedgehog and syndecans-3 coregulate chondrocyte proliferation and function during chick limb skeletogenesis.
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- Developmental Dynamics, 2004, v. 229, n. 3, p. 607
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- Article
Elevated inflammatory gene expression in intervertebral disc tissues in mice with ADAM8 inactivated.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81495-y
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Osteoarthritis and chronic pain: Interleukin-6 as a common denominator and therapeutic target.
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- Science Signaling, 2022, v. 15, n. 744, p. 1, doi. 10.1126/scisignal.add3702
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Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice.
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- Science Signaling, 2021, v. 14, n. 669, p. 1, doi. 10.1126/scisignal.abd0536
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HhAntag, a Hedgehog Signaling Antagonist, Suppresses Chondrogenesis and Modulates Canonical and Non-Canonical BMP Signaling.
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- Journal of Cellular Physiology, 2016, v. 231, n. 5, p. 1033, doi. 10.1002/jcp.25192
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Adenine nucleotide metabolism by chondrocytes in vitro: Role of ATP in chondrocyte maturation and matrix mineralization.
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- Journal of Cellular Physiology, 1995, v. 165, n. 3, p. 468, doi. 10.1002/jcp.1041650304
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Articular Cartilage Endurance and Resistance to Osteoarthritic Changes Require Transcription Factor Erg.
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- Arthritis & Rheumatology, 2015, v. 67, n. 10, p. 2679, doi. 10.1002/art.39243
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- Article