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- Title
Vitamin D: association with eosinophil counts and IgE levels in children with asthma.
- Authors
Castro Gomes de Amorim, Claudio Luiz; de Oliveira, Joice Mara; Rodrigues, Antenor; Couto Furlanetto, Karina; Pitta, Fabio
- Abstract
In this cross-sectional study, we investigated the relationship that levels of vitamin D had with eosinophil counts and IgE levels in 26 children with asthma (6-12 years of age) in the city of Londrina, Brazil. Vitamin D levels were found to correlate significantly, albeit moderately, with age (r = -0.51) and eosinophilia (r = -0.49), although not with IgE levels (r = -0.12). When we stratified the sample into two groups by the median vitamin D level (< or ≥ 24 ng/mL), we found that those in the < 24 ng/mL group were older, had higher eosinophil counts, and had higher IgE levels. To our knowledge, this is the first study to show an association between low levels of vitamin D and more pronounced eosinophilia in children with asthma in Brazil.
- Subjects
LONDRINA (Brazil); BRAZIL; VITAMIN D; ASTHMA in children; EOSINOPHILIA
- Publication
Brazilian Journal of Pulmonology / Jornal Brasileiro de Pneumologia, 2021, Vol 47, Issue 1, p1
- ISSN
1806-3713
- Publication type
Article
- DOI
10.36416/1806-3756/e20200279