We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Natural killer cell in the developing life.
- Authors
Lee, Yen-Chang; Lin, Syh-Jae
- Abstract
Natural killer (NK) cells that provide first-line innate immune reactions against virus-infected and tumor cells have different roles in different body sites and in different stages. From the beginning of life, NK cells participate in many aspects of development, especially in a successful pregnancy and a healthy neonatal stage. This article reviews recent advances regarding the role of NK cells in implantation, placentation and immune tolerance during pregnancy as well as in the neonatal immune defense. The interactions between NK cells and other immune cells in each developmental stage are discussed.
- Subjects
UTERUS physiology; IMMUNE system physiology; KILLER cells; PREGNANCY; VIRUS diseases; FETAL development
- Publication
Journal of Perinatal Medicine, 2015, Vol 43, Issue 1, p11
- ISSN
0300-5577
- Publication type
Article
- DOI
10.1515/jpm-2013-0244