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- Title
In Hospital Mortality in Acute Heart Failure with Idiopathic Cardiomyopathy and Type II Diabetes.
- Authors
Al Jarallah, Mohammed; Rajan, Rajesh; Dashti, Raja; Bulbanat, Bassam; Ridha, Mustafa; Sulaiman, Kadhim; Al-Mahmeed, Wael; Al-Saber, Ahmad; Kobalava, Zhanna; Panduranga, Prashanth; AlHabib, Khalid F.; Al Suwaidi, Jassim; Amin, Haitham; Alajmi, Salem Mohammed
- Abstract
Background: Clinical characteristics and outcomes in patients with Type 2 Diabetes (T2DM) and Acute Heart Failure (AHF) patients with idiopathic cardiomyopathy are not well known. Methods: We analysed data from 509 consecutive patients with idiopathic cardiomyopathy presenting with AHF to 47 hospitals in seven Middle Eastern countries (Saudi Arabia, Oman, Yemen, Kuwait, United Arab Emirates, Qatar and Bahrain) between February and November 2012. All patients were stratified according to T2DM. Analyses were performed using univariate and multivariate statistical techniques. Results: The mean age of the cohort was 52.0 +14.8 years. Of the 509 patients, 123 (24.2%) had T2DM and had a higher incidence of major stroke than the non-diabetic group (11.4% vs 2.8%; p=0.001). Diabetic patients were also more likely to be associated with hypertension than those without diabetes mellitus (78.9% vs 21.8%; p<0.001) Multivariate logistic regression demonstrated that those with cardiogenic shock (adjusted odds ratio (aOR), 59.3; 95% confidence interval (CI): 20.1-207; p=0.001) and non-invasive ventilation (NIV) (aOR, 4.19; 95% CI: 1.33-13.1; p=0.013) were associated with higher odds of all-cause in-hospital mortality. However, age (aOR, 1.00; 95% CI; 0.96-1.03; p=0.792), T2DM status (aOR, 0.43; 95% CI; 0.10-1.51; p=0.207), and atrial fibrillation (aOR, 3.95; 95% CI: 0.82-17.2; p=0.07) were not associated with higher odds of all-cause in-hospital mortality. Conclusion: In AHF patients with idiopathic cardiomyopathy, T2DM was not associated with higher odds of all-cause in-hospital mortality. Patients on NIV and cardiogenic shock were demonstrated as independent predictors of increased in-hospital mortality.
- Subjects
HOSPITAL mortality; HEART failure; CARDIOMYOPATHIES; TYPE 2 diabetes; CONFIDENCE intervals
- Publication
E Journal of Cardiovascular Medicine, 2023, Vol 11, p1
- ISSN
2147-1924
- Publication type
Article