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- Title
Bronchiectasis and Emphysema.
- Authors
Dimakou, Katerina; Chrysikos, Serafeim; Melachroinidou, Myrsini; Triantafillidou, Christina
- Abstract
Emphysema is the predominant component in alpha1-Antitrypsin (α1-AT) Deficiency, but the prevalence and impact of bronchiectasis is greater than previously recognized. Bronchiectasis is more common and severe where emphysema is seen and may add to the severity of the disease and worse health status. The pathogenetic association between bronchiectasis and emphysema is not well defined. Whether bronchiectasis take advantage of the α1-AT augmentation therapy remains unknown. The coexistence of emphysema and bronchiectasis in COPD patients is nor rare. Bronchiectasis could have an impact on disease course over and above the effects of emphysema. From the other side, the presence of emphysema in bronchiectasis is common and may contribute to the severity of airways obstruction. Emphysema may represent a risk factor of mortality in patients with bronchiectasis.
- Subjects
BRONCHIECTASIS; BRONCHIAL diseases
- Publication
Pneumon, 2016, Vol 29, Issue 4, p334
- ISSN
1105-848X
- Publication type
Article