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- Title
GLP-1 Receptor: A New Target for Sepsis.
- Authors
Yang, Fuxun; Zeng, Fan; Luo, Xiaoxiu; Lei, Yu; Li, Jiajia; Lu, Sen; Huang, Xiaobo; Lan, Yunping; Liu, Rongan
- Abstract
Patients with sepsis often exhibit hyperglycemia, which increases mortality. glucagon-like peptide-1 receptor agonists (GLP-1RAs) not only regulate blood glucose homeostasis but also improve organ dysfunction, regulate immunity, and control inflammation and other functions in patients with sepsis. Here, we review the possible application of GLP-1RAs in sepsis, to provide a new perspective for the clinical diagnosis and treatment of patients with sepsis complicated with stress hyperglycemia.
- Subjects
GLUCAGON-like peptide-1 receptor; SEPSIS; GLUCAGON-like peptide-1 agonists; BLOOD sugar; HOMEOSTASIS
- Publication
Frontiers in Pharmacology, 2021, Vol 12, p1
- ISSN
1663-9812
- Publication type
Article
- DOI
10.3389/fphar.2021.706908