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- Title
CELIAC DISEASE - PATHOPHYSIOLOGIC, DIAGNOSTIC AND DIETETIC ASPECTS.
- Authors
Maria, Fárr Ana; Adorján, Szabó István; Florina, Gliga Ioana; Monica, Tarcea; Zita, Fazakas; Vince, Fárr
- Abstract
Background: Celiac disease is an autoimmune, chronic inflammatory disease of the small intestine, induced by consumption of gluten containing cereals. It can be develop at any age in in genetically susceptible individuals, having a strongly HLA-association. The disease pathophysiology is based on the destruction of the small intestinal mucosa, by an autoimmune mechanism, induced by a gluten containing diet. Material and methods: We followed in 2017 a sample of 203 Romanian people who completed a consented questionnaire, with questions about the diagnostic methods, diet profile and gluten-free products sources. Results: In our sample, 71% started a gluten free diet after medical diagnosis of Celiac disease, and 29% suspected the existence of disease and started the diet without any medical advice. Starting gluten free diet based only on suspicion of Celiac disease can delay the diagnosis and the proper management of it. For a proper diagnosis there is necessary to identify special antibodies and a positive intestinal biopsy. Conclusion: We recommend implementation of proper education in schools and also training programs in order to sustain the importance of medical evaluation and analysis, and if the diagnosis is positive, start and follow a personalized gluten free diet. A special attention need to be paid by Celiac patients to presence of gluten as a food contaminant in their menu, and to avoid it.
- Subjects
CELIAC disease diagnosis; CELIAC disease; GLUTEN-free foods; GLUTEN-free diet; PATHOLOGICAL physiology; NUTRITION
- Publication
Acta Medica Marisiensis, 2018, Vol 64, p7
- ISSN
2068-3324
- Publication type
Article