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Stem Cells as Vehicles for Youthful Regeneration of Aged Tissues.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. Suppl_1, p. S39, doi. 10.1093/gerona/glu043
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- Article
GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34932-z
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- Article
Adult mouse astrocytes degrade amyloid-b in vitro and in situ.
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- Nature Medicine, 2003, v. 9, n. 4, p. 453, doi. 10.1038/nm838
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- Article
TGF-β1 promotes microglial amyloid-β clearance and reduces plaque burden in transgenic mice.
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- Nature Medicine, 2001, v. 7, n. 5, p. 612, doi. 10.1038/87945
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- Article
Ibuprofen, inflammation and Alzheimer disease.
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- Nature Medicine, 2000, v. 6, n. 9, p. 973, doi. 10.1038/79661
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- Article
Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice.
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- Journal of Neuroscience, 2004, v. 24, n. 10, p. 2527, doi. 10.1523/JNEUROSCI.4315-03.2004
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- Article
Plasma and CSF biomarkers of aging and cognitive decline in Caribbean vervets.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5460, doi. 10.1002/alz.14038
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- Article
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity‐dependent synaptic and microglial transcriptomic changes in a late‐stage Alzheimer's mouse model.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 7, p. 4434, doi. 10.1002/alz.13857
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- Article
Post‐translational modifications linked to preclinical Alzheimer's disease–related pathological and cognitive changes.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 1851, doi. 10.1002/alz.13576
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- Article
Neuronal stimulation‐regulated RNA splicing defects in tauopathies are corrected by treatment with a p75 NTR modulator.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.080548
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- Article
Proteo‐genomics of soluble TREM2 in cerebrospinal fluid provides novel insights for TREM2 biology and identifies novel modulators for Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077275
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- Article
Proteo‐genomics of soluble TREM2 in cerebrospinal fluid provides novel insights for TREM2 biology and identifies novel modulators for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077275
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- Article
p75<sup>NTR</sup> modulation counteracts alterations in neuronal and glial activity‐dependent profiles of gene co‐expression networks in tauopathy mice.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.066948
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- Article
CSF Biomarkers of Amyloid and Tau Pathologies in Participants Enrolled in the Stanford Alzheimer's Disease Research Center.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.068261
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- Article
Distinct cerebrospinal fluid immune perturbations in healthy brain aging and cognitive impairment.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.069384
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- Article
Exploring lysosomal defects and rescue strategies for Alzheimer's disease using human transdifferentiated neurons.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.063964
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- Article
Targeting VCAM1 to reduce neuroinflammation in ischemia‐triggered vascular dementia.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053849
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- Article
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease: Molecular and cell biology: Inflammatory and microglia‐mediated mechanisms in AD.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044082
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- Article
Undulating changes in human plasma proteome profiles across the lifespan are linked to disease: Biomarkers (non‐neuroimaging): Novel biomarkers.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043868
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- Article
O5‐05‐05: UNDULATIONS OF THE PLASMA PROTEOME DEFINE DISTINCT STAGES OF HUMAN LIFESPAN AND REVEAL ACCELERATED AGING IN ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1628, doi. 10.1016/j.jalz.2019.06.4862
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- Article
O4‐09‐06: CLONALLY EXPANDED CD8 T CELLS PATROL ALZHEIMER'S CEREBROSPINAL FLUID.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1257, doi. 10.1016/j.jalz.2019.06.4793
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- Article
P3‐048: ANTI‐INFLAMMATORY SMALL MOLECULE SRI‐011381 FOR THE TREATMENT OF NEURODEGENERATION AND ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P944, doi. 10.1016/j.jalz.2019.06.3074
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- Article
The immunology of neurodegeneration.
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- Journal of Clinical Investigation, 2012, v. 122, n. 4, p. 1156, doi. 10.1172/JCI58656
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- Article
Angiotensin II sustains brain inflammation in mice via TGF-beta.
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- 2010
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- Publication type:
- journal article
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
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- 2008
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- journal article
Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis.
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- 2007
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- Publication type:
- journal article
Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis.
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- Journal of Clinical Investigation, 2007, v. 117, n. 11, p. 3306, doi. 10.1172/JCI31763
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- Article
Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.
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- 2006
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- Publication type:
- journal article
Deficiency in neuronal TGF-β signaling promotes, neurodegeneration and Alzheimer's pathology.
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- Journal of Clinical Investigation, 2006, v. 116, n. 11, p. 3060, doi. 10.1172/JCI27341
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- Article
Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues.
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- Nature Biotechnology, 2024, v. 42, n. 1, p. 109, doi. 10.1038/s41587-023-01751-6
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- Article
Targeting autophagy for disease therapy.
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- Nature Biotechnology, 2013, v. 31, n. 4, p. 322, doi. 10.1038/nbt.2554
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- Article
β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis.
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- Nature Medicine, 2015, v. 21, n. 8, p. 932, doi. 10.1038/nm.3898
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- Article
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.
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- Nature Medicine, 2014, v. 20, n. 6, p. 659, doi. 10.1038/nm.3569
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- Article
Identification of a central role for complement in osteoarthritis.
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- Nature Medicine, 2011, v. 17, n. 12, p. 1674, doi. 10.1038/nm.2543
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- Article
Immune cells may fend off Alzheimer disease.
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- Nature Medicine, 2007, v. 13, n. 4, p. 408, doi. 10.1038/nm0407-408
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- Article
Inflammation in Alzheimer disease: driving force, bystander or beneficial response?
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- Nature Medicine, 2006, v. 12, n. 9, p. 1005, doi. 10.1038/nm1484
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- Article
Killing pain, killing neurons?
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- Nature Medicine, 2005, v. 11, n. 5, p. 472, doi. 10.1038/nm0505-472
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- Publication type:
- Article
The future of blood-based biomarkers for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, n. 1, p. 115, doi. 10.1016/j.jalz.2013.01.013
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- Article
A longitudinal study of aging and the development of Alzheimer's disease in people with Down syndrome
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- 2012
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- Abstract
Plasma proteomics as a discovery tool for novel pathways in neurodegenerative diseases
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- 2012
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- Publication type:
- Abstract
Immune and injury response in neurodegeneration
- Published in:
- 2011
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- Abstract
Potential early diagnosis of Alzheimers disease using changes of the enteric nervous system
- Published in:
- 2010
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- Abstract
P2-294: Microarray profiling reveals autoantibody reactivities against abnormal amyloid peptide conformations decline with age and in Alzheimer's disease
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- 2008
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- Publication type:
- Abstract
P1-413: Collagen VI protects neurons against amyloid-beta toxicity
- Published in:
- 2008
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- Publication type:
- Abstract
‘S1-03-04: The autophagy protein Beclin 1 is reduced in early Alzheimer's disease and regulates Abeta accumulation in vivo
- Published in:
- 2008
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- Publication type:
- Abstract
S2-02-04: Plasma protein biomarkers to predict early Alzheimer’s disease
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- 2007
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- Publication type:
- Abstract
O4-05-02: Deficiency of the Beclin 1 autophagy protein promotes Alzheimer’s disease pathology
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- 2006
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- Abstract
O4-05-02: Deficiency of the Beclin 1 autophagy protein promotes Alzheimer’s disease pathology
- Published in:
- 2006
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- Publication type:
- Abstract
Transforming growth factor-β signaling pathway as a therapeutic target in neurodegeneration.
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- Journal of Molecular Neuroscience, 2004, v. 24, n. 1, p. 149, doi. 10.1385/JMN:24:1:149
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- Article
Thy1-hAPP<sup>Lond/Swe+</sup> mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function.
- Published in:
- Brain & Behavior, 2012, v. 2, n. 2, p. 142, doi. 10.1002/brb3.41
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- Article