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- Title
Poor prognosis after lower‐limb amputation irrespective of diabetes status in patients undergoing hemodialysis.
- Authors
Tamaki, Akira; Kitamura, Mineaki; Yamaguchi, Kosei; Notomi, Satoko; Tomura, Hideyuki; Sawase, Kenji; Hashiguchi, Junichiroh; Harada, Takashi; Funakoshi, Satoshi; Takazono, Takahiro; Mukae, Hiroshi; Nishino, Tomoya
- Abstract
Introduction: Diabetes mellitus is one of the most important risk factors for lower‐limb amputation in patients undergoing hemodialysis. However, the influence of diabetes mellitus on survival after lower‐limb amputation is unknown. Methods: Patients who underwent lower‐limb amputation since 1996 (amputation group) and those who underwent hemodialysis during 2011–2012 (control group) were included and were followed up until July 2022. Results: There were 70 patients (age: 66.3 ± 8.2 years, 80% male, 77% diabetic) in the amputation group and 328 (age: 67.5 ± 13.5 years, 56% male, 33% diabetic) in the control group. The amputation group showed a poorer prognosis than the control group (hazard ratio [HR]: 2.41, p < 0.001). In the control group, patients with diabetes exhibited poorer survival than those without diabetes (HR: 1.86, p < 0.001). In the amputation group, patients with diabetes exhibited improved survival (HR: 0.47, p = 0.02). Conclusion: Patients undergoing hemodialysis who underwent lower‐limb amputation exhibited a poor prognosis, irrespective of diabetes status.
- Subjects
LEG amputation; TRAUMATIC amputation; AMPUTATION; PEOPLE with diabetes; HEMODIALYSIS patients; PROGNOSIS; DIABETES
- Publication
Therapeutic Apheresis & Dialysis, 2023, Vol 27, Issue 3, p495
- ISSN
1744-9979
- Publication type
Article
- DOI
10.1111/1744-9987.13947