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- Title
Selective Adsorption of Human CD4<sup>+</sup> T Cells.
- Authors
Matsuo, Hidenori; Goto, Hirofumi; Kambara, Chiaki; Fukudome, Takayasu; Mizota, Takamitsu; Onodera, Hirokazu; Yoshida, Makoto; Shibuya, Noritoshi
- Abstract
Reports on the design of a column in which an anti-CD4 antibody was immobilized on the activated substance to remove CD4+ T cells selectively from circulation. Selective adsorption of the CD4+ T cells from whole blood; Resulting depletion of the antigen-specific T cell responses; Conclusion that the column would be potentially useful for treatment of T cell-mediated autoimmune diseases.
- Subjects
CD4 antigen; T cells; BLOOD; BLOOD cells; ADSORPTION (Chemistry); AUTOIMMUNE diseases
- Publication
Therapeutic Apheresis & Dialysis, 2004, Vol 8, Issue 3, p194
- ISSN
1744-9979
- Publication type
Article
- DOI
10.1111/j.1526-0968.2004.00146.x