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Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.
Published in:
Journal of Extracellular Vesicles, 2015, v. 4, p. 1, doi. 10.3402/jev.v4.26316
By:
- Wiklander, Oscar P. B.;
- Nordin, Joel Z.;
- O'Loughlin, Aisling;
- Gustafsson, Ylva;
- Corso, Giulia;
- Mäger, Imre;
- Vader, Pieter;
- Lee, Yi;
- Sork, Helena;
- Seow, Yiqi;
- Heldring, Nina;
- Alvarez-Erviti, Lydia;
- Smith, CI Edvard;
- Le Blanc, Katarina;
- Macchiarini, Paolo;
- Jungebluth, Philipp;
- Wood, Matthew J. A.;
- Andaloussi, Samir EL
Publication type:
Article
Generalizable anchor aptamer strategy for loading nucleic acid therapeutics on exosomes.
Published in:
EMBO Molecular Medicine, 2024, v. 16, n. 4, p. 1027, doi. 10.1038/s44321-024-00049-7
By:
- Han, Gang;
- Zhang, Yao;
- Zhong, Li;
- Wang, Biaobiao;
- Qiu, Shuai;
- Song, Jun;
- Lin, Caorui;
- Zou, Fangdi;
- Wu, Jingqiao;
- Yu, Huanan;
- Liang, Chao;
- Wen, Ke;
- Seow, Yiqi;
- Yin, HaiFang
Publication type:
Article
Clinical performance of Roche cobas 6800, Luminex ARIES, MiRXES Fortitude Kit 2.1, Altona RealStar, and Applied Biosystems TaqPath for SARS‐CoV‐2 detection in nasopharyngeal swabs.
Published in:
Journal of Medical Virology, 2021, v. 93, n. 7, p. 4603, doi. 10.1002/jmv.26940
By:
- Lee, Chun Kiat;
- Tham, Jason Wei Ming;
- Png, Siyu;
- Chai, Chean Nee;
- Ng, Shu Chi;
- Tan, Eunice Jia Min;
- Ng, Li Jie;
- Chua, Rui Ping;
- Sani, Musa;
- Seow, Yiqi;
- Yan, Gabriel;
- Tang, Julian
Publication type:
Article
Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7.
Published in:
Nucleic Acids Research, 2017, v. 45, n. 13, p. 7870, doi. 10.1093/nar/gkx483
By:
- Curtis, Helen J.;
- Yiqi Seow;
- Wood, Matthew J. A.;
- Varela, Miguel A.
Publication type:
Article
Functional VEGFA knockdown with artificial 3'-tailed mirtrons defined by 5' splice site and branch point.
Published in:
Nucleic Acids Research, 2015, v. 43, n. 13, p. 6568, doi. 10.1093/nar/gkv617
By:
- Kian Hong Kock;
- Kiat Whye Kong;
- Shawn Hoon;
- Yiqi Seow
Publication type:
Article
Silencing of Parkinson's disease-associated genes with artificial mirtron mimics of miR-1224.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 19, p. 9863, doi. 10.1093/nar/gks712
By:
- Sibley, Christopher R.;
- Seow, Yiqi;
- Curtis, Helen;
- Weinberg, Marc S.;
- Wood, Matthew J. A.
Publication type:
Article
The biogenesis and characterization of mammalian microRNAs of mirtron origin.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 1, p. 438, doi. 10.1093/nar/gkr722
By:
- Sibley, Christopher R.;
- Seow, Yiqi;
- Saayman, Sheena;
- Dijkstra, Krijn K.;
- El Andaloussi, Samir;
- Weinberg, Marc S.;
- Wood, Matthew J. A.
Publication type:
Article
Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science.
Published in:
Nature Biotechnology, 2013, v. 31, n. 10, p. 908, doi. 10.1038/nbt.2671
By:
- Guerette, Paul A;
- Hoon, Shawn;
- Seow, Yiqi;
- Raida, Manfred;
- Masic, Admir;
- Wong, Fong T;
- Ho, Vincent H B;
- Kong, Kiat Whye;
- Demirel, Melik C;
- Pena-Francesch, Abdon;
- Amini, Shahrouz;
- Tay, Gavin Z;
- Ding, Dawei;
- Miserez, Ali
Publication type:
Article
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes.
Published in:
Nature Biotechnology, 2011, v. 29, n. 4, p. 341, doi. 10.1038/nbt.1807
By:
- Alvarez-Erviti, Lydia;
- Yiqi Seow;
- HaiFang Yin;
- Betts, Corinne;
- Lakhal, Samira;
- Wood, Matthew J. A.
Publication type:
Article
Cardio‐respiratory and phenotypic rescue of dystrophin/utrophin‐deficient mice by combination therapy.
Published in:
EMBO Reports, 2022, v. 23, n. 6, p. 1, doi. 10.15252/embr.202153955
By:
- Lin, Caorui;
- Han, Gang;
- Jia, Lulu;
- Zhao, Yiwen;
- Song, Jun;
- Ran, Ning;
- Yokota, Toshifumi;
- Seow, Yiqi;
- Yin, HaiFang
Publication type:
Article
Ca<sup>2+</sup> Influx through Mechanosensitive Channels Inhibits Neurite Outgrowth in Opposition to Other Influx Pathways and Release from Intracellular Stores.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 21, p. 5656, doi. 10.1523/JNEUROSCI.0675-06.2006
By:
- Jacques-Fricke, Bridget T.;
- Yiqi Seow;
- Gottlieb, Philip A.;
- Sachs, Frederick;
- Gomez, Timothy M.
Publication type:
Article
Smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts.
Published in:
Molecular Medicine Reports, 2020, v. 22, n. 6, p. 4589, doi. 10.3892/mmr.2020.11549
By:
- CHEN FAN;
- EL ANDALOUSSI, SAMIR;
- TAAVI LEHTO;
- KIAT WHYE KONG;
- YIQI SEOW
Publication type:
Article
Towards a Rapid-Turnaround Low-Depth Unbiased Metagenomics Sequencing Workflow on the Illumina Platforms.
Published in:
Bioengineering (Basel), 2023, v. 10, n. 5, p. 520, doi. 10.3390/bioengineering10050520
By:
- Koh, Winston Lian Chye;
- Poh, Si En;
- Lee, Chun Kiat;
- Chan, Tim Hon Man;
- Yan, Gabriel;
- Kong, Kiat Whye;
- Lau, Lalita;
- Lee, Wai Yip Thomas;
- Cheng, Clark;
- Hoon, Shawn;
- Seow, Yiqi
Publication type:
Article
Hexose enhances oligonucleotide delivery and exon skipping in dystrophin-deficient mdx mice.
Published in:
Nature Communications, 2016, v. 7, n. 3, p. 10981, doi. 10.1038/ncomms10981
By:
- Han, Gang;
- Gu, Ben;
- Cao, Limin;
- Gao, Xianjun;
- Wang, Qingsong;
- Seow, Yiqi;
- Zhang, Ning;
- Wood, Matthew J. A.;
- Yin, HaiFang
Publication type:
Article
Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy.
Published in:
Science Translational Medicine, 2018, v. 10, n. 444, p. 1, doi. 10.1126/scitranslmed.aat0195
By:
- Gao, Xianjun;
- Ran, Ning;
- Dong, Xue;
- Zuo, Bingfeng;
- Yang, Rong;
- Zhuo, Qibing;
- Moulton, Hong M.;
- Seow, Yiqi;
- Yin, HaiFang
Publication type:
Article
fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.
Published in:
Human Molecular Genetics, 2019, v. 28, n. 4, p. 699, doi. 10.1093/hmg/ddy377
By:
- Yin, HaiFang;
- Moulton, Hong M;
- Betts, Corinne;
- Seow, Yiqi;
- Boutilier, Jordan;
- Iverson, Patrick L;
- Wood, Matthew J A
Publication type:
Article
Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice.
Published in:
Molecular Therapy, 2011, v. 19, n. 7, p. 1295, doi. 10.1038/mt.2011.79
By:
- HaiFang Yin;
- Saleh, Amer F.;
- Betts, Corinne;
- Camelliti, Patrizia;
- Yiqi Seow;
- Ashraf, Shirin;
- Arzumanov, Andrey;
- Hammond, Suzan;
- Merritt, Thomas;
- Gait, Michael J.;
- Wood, Matthew J. A.
Publication type:
Article
Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO.
Published in:
Molecular Therapy, 2010, v. 18, n. 10, p. 1822, doi. 10.1038/mt.2010.151
By:
- HaiFang Yin;
- Moulton, Hong M.;
- Betts, Corinne;
- Merritt, Thomas;
- Seow, Yiqi;
- Ashraf, Shirin;
- QingSong Wang;
- Boutilier, Jordan;
- Wood, Matthew J. A.
Publication type:
Article
Optimization of Peptide Nucleic Acid Antisense Oligonucleotides for Local and Systemic Dystrophin Splice Correction in the mdx Mouse.
Published in:
Molecular Therapy, 2010, v. 18, n. 4, p. 819, doi. 10.1038/mt.2009.310
By:
- HaiFang Yin;
- Betts, Corinne;
- Saleh, Amer F.;
- Ivanova, Gabriela D.;
- Hyunil Lee;
- Yiqi Seow;
- Kim, Dalsoo;
- Gait, Michael J.;
- Wood, Matthew J.A.
Publication type:
Article
Novel RNA-based Strategies for Therapeutic Gene Silencing.
Published in:
Molecular Therapy, 2010, v. 18, n. 3, p. 466, doi. 10.1038/mt.2009.306
By:
- Sibley, Christopher R.;
- Yiqi Seow;
- Wood, Matthew J. A.
Publication type:
Article
Biological Gene Delivery Vehicles: Beyond Viral Vectors.
Published in:
Molecular Therapy, 2009, v. 17, n. 5, p. 767, doi. 10.1038/mt.2009.41
By:
- Yiqi Seow;
- Wood, Matthew J.
Publication type:
Article
Sub genomic analysis of SARS-CoV-2 using short read amplicon-based sequencing.
Published in:
Frontiers in Genetics, 2023, v. 14, p. 1, doi. 10.3389/fgene.2023.1086865
By:
- Lian Chye Winston Koh;
- Yiqi Seow;
- Kiat Whye Kong;
- Ming Li Lalita Lau;
- Kumar, Shoban Krishna;
- Yan, Gabriel;
- Chun Kiat Lee;
- Yan, Benedict;
- Tambyah, Paul Anantharajah;
- Hoon, Shawn
Publication type:
Article
Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 3, p. 413, doi. 10.1093/hmg/ddq477
By:
- Crisp, Alastair;
- Yin, HaiFang;
- Goyenvalle, Aurelie;
- Betts, Corinne;
- Moulton, Hong M.;
- Seow, Yiqi;
- Babbs, Arran;
- Merritt, Thomas;
- Saleh, Amer F.;
- Gait, Michael J.;
- Stuckey, Daniel J.;
- Clarke, Kieran;
- Davies, Kay E.;
- Wood, Matthew J.A.
Publication type:
Article
A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 22, p. 4405, doi. 10.1093/hmg/ddp395
By:
- Yin, HaiFang;
- Moulton, Hong M.;
- Betts, Corinne;
- Seow, Yiqi;
- Boutilier, Jordan;
- Iverson, Patrick L.;
- Wood, Matthew J.A.
Publication type:
Article
Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.
Published in:
Human Molecular Genetics, 2008, v. 17, n. 24, p. 3909, doi. 10.1093/hmg/ddn293
By:
- Yin, HaiFang;
- Moulton, Hong M.;
- Seow, Yiqi;
- Boyd, Corinne;
- Boutilier, Jordan;
- Iverson, Patrick;
- Wood, Matthew J.A.
Publication type:
Article
Universal immunotherapeutic strategy for hepatocellular carcinoma with exosome vaccines that engage adaptive and innate immune responses.
Published in:
Journal of Hematology & Oncology, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13045-022-01266-8
By:
- Zuo, Bingfeng;
- Zhang, Yang;
- Zhao, Kangjie;
- Wu, Li;
- Qi, Han;
- Yang, Rong;
- Gao, Xianjun;
- Geng, Mengyuan;
- Wu, Yingjie;
- Jing, Renwei;
- Zhou, Qibing;
- Seow, Yiqi;
- Yin, HaiFang
Publication type:
Article

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