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- Title
The blood virome of 10,585 individuals from the ChinaMAP.
- Authors
Guo, Jia; Huang, Xuanlin; Zhang, Chenxi; Huang, Peide; Li, Yinhu; Wen, Fang; Wang, Xiaoji; Yang, Nanshan; Xu, Min; Bi, Yufang; Ning, Guang; Li, Lin; Wang, Weiqing; Cao, Yanan
- Abstract
We speculate that the I ACR i rs79314756 variant might enhance the activity of acrosin, thus facilitating the cleavage of C3 protein and promoting HHV6 virus transmission via the binding of membrane cofactor protein and oocyte receptors[13]. In addition, numerous common cancers are associated with oncogenic viruses, including Epstein-Barr virus (EBV), hepatitis B and C viruses (HBV and HCV), and human papillomavirus (HPV)[2]. These authors contributed equally: Jia Guo, Xuanlin Huang, Chenxi Zhang Dear Editor, Understanding the composition of human blood virome is essential for safe blood transfusions and infectious disease surveillance and control. Left: red bars represent the integration sites of HBV-B, and blue bars represent the integration sites of HBV-C. Right: the dark blue histogram represents the integration sites in HBV genome, and the light blue histogram represents the viral genome coverage.
- Subjects
EPSTEIN-Barr virus; MISSENSE mutation; MEDICAL sciences; ONCOGENIC viruses; PROTEIN structure prediction
- Publication
Cell Discovery, 2022, Vol 8, Issue 1, p1
- ISSN
2056-5968
- Publication type
Article
- DOI
10.1038/s41421-022-00476-1