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- Title
Split liver transplantation for retroperitoneal immature teratoma masquerading as hepatoblastoma.
- Authors
Oh, Dongkyu; Yi, Nam‐Joon; Song, Sanghee; Kim, Ok Kyung; Hong, Suk Kyun; Yoon, Kyung Chul; Ahn, Sung Woo; Kim, Hyo‐Sin; Kim, Hyeyoung; Kim, Hyun‐Young; Kang, Hyoung Jin; Lee, Myungsu; Lee, Kyoung Bun; Lee, Kwang‐Woong; Suh, Kyung Suk
- Abstract
Extragonadal teratoma originating from the retroperitoneum represents less than 5% of all teratomas and accounts for less than 10% of all pediatric retroperitoneal neoplasms. To date, there has been no report of teratoma managed with LT. This study reports an infant aged 3 months with retroperitoneal immature teratoma involving the hepatic hilum, refractory to chemotherapy and treated with LT. The patient was referred to our hospital for management of a growing abdominal mass. Histopathology of a fine needle biopsy of the lesion suggested the possibility of a hepatoblastoma with teratoid features. Cisplatin-based chemotherapy was initiated, but rapid growth of the tumor encasing the hepatic artery proper was detected, even after two cycles of chemotherapy. A split LT was carried out, and pathological examination of the explanted liver revealed the involvement of numerous neuroepithelial components, confirming the diagnosis of a Norris grade 3 immature teratoma. The patient recovered well and was discharged on day 19 post-LT. As on date, on postoperative day 240, he has completed seven cycles of a 12-cycle vinblastine and doxorubicin-based adjuvant chemotherapy.
- Subjects
LIVER transplantation; RETROPERITONEAL fibrosis; TERATOMA; RETROPERITONEUM; HISTOPATHOLOGY
- Publication
Pediatric Transplantation, 2017, Vol 21, Issue 7, pn/a
- ISSN
1397-3142
- Publication type
Article
- DOI
10.1111/petr.13025