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- Title
Predictive value of the area-under-the-concentration-time curve (AUC) in blood and in saliva for the toxicity of 5-fluorouracil(5-FU)/folinic acid in the treatment of colorectal cancer.
- Authors
Jansman, F.G.A.; Coenen, J.L.L.M.; Brouwers, J.R.B.J.
- Abstract
Investigates the use of fluorouracil (FU) and folinic acid in the treatment of colorectal carcinoma. Relationship between the toxicity of 5-FU-folinic acid and area-under-the-concentration-time (AUC) curve in blood; Intravenous administration of folinic acid; Association of AUC for saliva with FU toxicity.
- Subjects
ANTINEOPLASTIC agents; INTRAVENOUS injections
- Publication
British Journal of Clinical Pharmacology, 2000, Vol 50, Issue 5, p497
- ISSN
0306-5251
- Publication type
Article