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- Title
Ischaemic cholangiopathy and sickle cell disease.
- Authors
Ahmed, Mansoor; Dick, Moira; Mieli-Vergani, Giorgina; Harrison, Phil; Karani, John; Dhawan, Anil
- Abstract
We report a case of a 6-year-old girl of Afro-Caribbean origin, known to have sickle cell disease (SCD), with recurrent history of jaundice and abdominal pain. She was extensively investigated, including endoscopic retrograde cholangiopancreatography (ERCP), which revealed diffuse cholangiopathy of both extrahepatic and intrahepatic bile ducts. A pigtail stent was placed and balloon dilatation was performed for stricture of the extrahepatic duct. Since then, she remains well and asymptomatic. We suggest that cholangiopathy is the consequence of sickling in the end arteries of the biliary arterial tree.
- Subjects
SICKLE cell anemia; BLOOD diseases; BLOOD hyperviscosity syndrome; ABDOMINAL pain; JAUNDICE; ISCHEMIA diagnosis; ISCHEMIA treatment; BILE ducts; CHOLESTASIS; CATHETERIZATION; SURGICAL stents; DISEASE complications; DIAGNOSIS; THERAPEUTICS
- Publication
European Journal of Pediatrics, 2006, Vol 165, Issue 2, p112
- ISSN
0340-6199
- Publication type
journal article
- DOI
10.1007/s00431-005-0005-z