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i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44985-x
By:
- Romei, Matthew G.;
- Leonard, Brandon;
- Katz, Zachary B.;
- Le, Daniel;
- Yang, Yanli;
- Day, Eric S.;
- Koo, Christopher W.;
- Sharma, Preeti;
- Bevers III, Jack;
- Kim, Ingrid;
- Dai, Huiguang;
- Farahi, Farzam;
- Lin, May;
- Shaw, Andrey S.;
- Nakamura, Gerald;
- Sockolosky, Jonathan T.;
- Lazar, Greg A.
Publication type:
Article
Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.
Published in:
FEBS Journal, 2013, v. 280, n. 8, p. 1818, doi. 10.1111/febs.12206
By:
- Pellegrini, Maria;
- Willen, Laure;
- Perroud, Mai;
- Krushinskie, Dennis;
- Strauch, Kathy;
- Cuervo, Hernan;
- Day, Eric S.;
- Schneider, Pascal;
- Zheng, Timothy S.
Publication type:
Article
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19974-5
By:
- Ferri, Elena;
- Le Thomas, Adrien;
- Wallweber, Heidi Ackerly;
- Day, Eric S.;
- Walters, Benjamin T.;
- Kaufman, Susan E.;
- Braun, Marie-Gabrielle;
- Clark, Kevin R.;
- Beresini, Maureen H.;
- Mortara, Kyle;
- Chen, Yung-Chia A.;
- Canter, Breanna;
- Phung, Wilson;
- Liu, Peter S.;
- Lammens, Alfred;
- Ashkenazi, Avi;
- Rudolph, Joachim;
- Wang, Weiru
Publication type:
Article

Found: 3

i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists.

Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.

Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.