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- Title
Acid trip: Let's retire the terms "disproportionate hyper/hypochloremia" for electrolyte‐based acid–base derangements.
- Authors
Nolen‐Walston, Rose; Sharkey, Leslie
- Abstract
Excess bicarbonate is expelled via alveolar ventilation as carbon dioxide, causing a reduction in plasma bicarbonate concentration. gl Let us provide a slightly more complex example. Acid trip: Let's retire the terms "disproportionate hyper/hypochloremia" for electrolyte-based acid-base derangements The serum chemistry analysis now reveals a low bicarbonate concentration, not as a cause of the metabolic acidosis, but because of the hyponatremia and subsequent low SID acidosis (Figure 2B). With this, the dominant paradigm in acid-base physiology shifted to a bicarbonate-carbon dioxide model, where it remained for many decades.[1] The idea of electrolyte anions and cations as determinants of acid-base was all but forgotten.
- Subjects
ACID-base imbalances; CLINICAL chemistry; VETERINARY clinical pathology
- Publication
Veterinary Clinical Pathology, 2023, Vol 52, Issue 2, p204
- ISSN
0275-6382
- Publication type
Article
- DOI
10.1111/vcp.13264