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- Title
Cytokine-driven beta-cell production in vivo.
- Authors
Worchel, Hannah N; Magnuson, Mark A
- Abstract
The authors discuss a study by L. Baeyens and colleagues on the administration of epidermal growth factor (EGF) and ciliary neurotrophic factor (CNTF) to diabetic mice with stable pancreatic acinar cells conversion. They say that pancreatic cells are considered in cellular identities treatment which does not change in normal physiological settings. They mention the molecular mechanisms provided by the authors such as the genetic ablation of Stat3, a signaling protein.
- Subjects
EPIDERMAL growth factor; CILIARY neurotrophic factor; LABORATORY mice; PANCREATIC acinar cells; PROTEINS
- Publication
Nature Biotechnology, 2014, Vol 32, Issue 1, p63
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt.2788