We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A new kalihinol diterpene from the Hainan sponge Acanthella sp.
- Authors
Sun, Ji-Zheng; Chen, Kao-Shan; Yao, Li-gong; Liu, Hai-Li; Guo, Yue-Wei
- Abstract
A new kalihinol diterpene, 10- epi-kalihinol X ( 1), together with two known related diterpenes ( 2 and 3), and two sesquiterpenes ( 4 and 5) were isolated from the Hainan sponge Acanthella sp. The structure of the new compound was elucidated on the basis of the detailed analysis of its spectroscopic data and by comparison of its NMR data with those of structurally related compounds. Compounds 1 and 3–5 exhibited in vitro moderate cytotoxicities against human lung adenocarcinoma cell line A549, with IC50 values of 9.30, 3.17, 2.44, and 1.98 µg/mL, respectively.
- Publication
Archives of Pharmacal Research, 2009, Vol 32, Issue 11, p1581
- ISSN
0253-6269
- Publication type
Article
- DOI
10.1007/s12272-009-2110-4