We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Sites of invasion of cancer of the external auditory canal predicting oncologic outcomes.
- Authors
Shiga, Kiyoto; Nibu, Ken‐ichi; Fujimoto, Yasushi; Asakage, Takahiro; Homma, Akihiro; Mitani, Hiroki; Ogawa, Takenori; Okami, Kenji; Murono, Shigeyuki; Hirano, Shigeru; Ueda, Tsutomu; Hanai, Nobuhiro; Tsukahara, Kiyoaki; Ota, Ichiro; Yoshimoto, Seiichi; Shinozaki, Takeshi; Iwae, Shigemichi; Katagiri, Katsunori; Saito, Daisuke; Kiyota, Naomi
- Abstract
Background: This study aimed to reveal the influence of the invasion site of external auditory canal (EAC) cancer by analyzing the outcome of patients with advanced tumor. Methods: A total of 111 patients with T4 EAC cancer were enrolled in this study. Of these patients, 79 underwent chemoradiotherapy and 32 underwent surgery under curative intent. Univariate and multivariate analyses and the Kaplan–Meier method were used to focus on the tumor invasion sites and overall survival of the patients. Results: The 3‐year overall survival rate of all patients was 55.0%. In multivariate analysis, the only significant invasion site for overall survival was the facial nerve, with the dura mater being the next most influential site. When Kaplan–Meier survival curve was calculated, facial nerve and dura mater were the significant factors resulting in poor patient outcomes. Conclusion: The facial nerve and dura mater are crucial sites of EAC cancer for patient outcomes.
- Subjects
EAR canal; OVERALL survival; SURVIVAL rate; DURA mater; FACIAL nerve
- Publication
Head & Neck, 2021, Vol 43, Issue 10, p3097
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.26800