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- Title
Hepatitis B virus-related polyarteritis nodosa and membranous nephropathy.
- Authors
Mouthon, Luc; Deblois, Pierre; Sauvaget, Françoise; Meyrier, Alain; Callard, Patrice; Guillevin, Loïc; Mouthon, L; Deblois, P; Sauvaget, F; Meyrier, A; Callard, P; Guillevin, L
- Abstract
We report the case of man with a history of post-transfusion chronic persistent hepatitis due to hepatitis B virus (HBV), who secondarily developed polyarteritis nodosa (PN) and membranous nephropathy (MN) simultaneously. At that time, liver biopsy yielded the diagnosis of active chronic hepatitis, and serological tests showed a high replication rate of HBV. PN was due to HBV infection, but the etiology of MN was uncertain, as it has never been described in PN, even in its microscopic form. There was no evidence of paraneoplastic syndrome or other causes of MN. Although the renal biopsy did not give any indication of HBV-related glomerulonephritis, the patient was considered to have an association of classic PN and MN, both related to HBV. Treatment combined plasmapheresis and interferon-alpha.
- Publication
American Journal of Nephrology, 1995, Vol 15, Issue 3, p266
- ISSN
0250-8095
- Publication type
journal article
- DOI
10.1159/000168844