We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Proteus Syndrome with Neurological Manifestations: A Rare Presentation.
- Authors
Sachdeva, Pallavi; Minocha, Priyanka; Jain, Rohit; Sitaraman, Sadasivan; Goyal, Manisha
- Abstract
Proteus syndrome (PS) is an extremely rare and complex disorder. Approximately 200 cases have been reported, and it seems to affect people of all ethnic and racial groups. PS is characterized by segmental overgrowth of multiple tissues and organs including vascular malformations, lipomatous overgrowth, hyperpigmentation, and various types of nevi. We hereby present a 7‑year‑old boy who presented with seizures and overgrowth of one‑half of the body. Although classical physical features have been described, epilepsy and other neurological manifestations are rarely reported features of PS. Early detection of association of epilepsy and hemimegalencephaly with PS can prevent/minimize the neurological complications, disability, morbidity, and mortality.
- Subjects
PROTEUS syndrome; NEURAL development; SEIZURES (Medicine); EPILEPSY; GROWTH disorders; NEUROLOGIC manifestations of general diseases; SPASMS; CEREBRAL cortex abnormalities; DIAGNOSIS
- Publication
Journal of Pediatric Neurosciences, 2017, Vol 12, Issue 1, p109
- ISSN
1817-1745
- Publication type
Article
- DOI
10.4103/jpn.JPN_139_16