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- Title
Pattern of Congenital Anomalies in Newborn: A 4-Year Surveillance of Newborns Delivered in a Tertiary Healthcare Facility in the South-East Nigeria.
- Authors
Ekwochi, Uchenna; Asinobi, Isaac Nwabueze; Osuorah, Donatus Chidiebere Ignatius; Ndu, Ikenna Kingsley; Ifediora, Christain; Amadi, Ogechukwu F; Sunday Mba, Gabriel
- Abstract
Congenital abnormalities are important causes of morbidity and mortality in children and significantly add to the burdens on healthcare in developing countries. Unfortunately, there remains a paucity of information on congenital birth defects in most developing countries. This is a 4-year prospective study that assessed the patterns and predictors of congenital anomalies among newborns at the Enugu State University Teaching Hospital, Nigeria. In total, 5830 deliveries were recorded, of which 38 had congenital anomalies, giving an incidence rate of 6.5/1000 live births. Fifty-two newborns were enrolled as nested controls. Factors significantly associated with congenital anomalies were low birth weight (p = 0.009), low socio-economic class (p = 0.011), lower maternal educational attainment (p = 0.009), parity of ≥ 5 (p = 0.002), febrile illness (p = 0.001) and the use of local concoction in index pregnancy (p = 0.009). More than half of the anomalies reported involved the musculoskeletal system. Occurrence of congenital anomalies may be prevented by curtailing risk factors identified in this study.
- Subjects
NIGERIA; CONGENITAL disorders; NEWBORN infants; MEDICAL care; INFANTS; PATHOLOGY; HUMAN abnormalities; LOW birth weight; DELIVERY (Obstetrics); EXTREMITIES (Anatomy); NEWBORN screening; INFANT mortality; LONGITUDINAL method; MATERNAL age; EVALUATION of medical care; NEURAL tube defects; PREGNANCY; PREGNANCY complications; QUESTIONNAIRES; SPECIALTY hospitals; DISEASE incidence; TERTIARY care
- Publication
Journal of Tropical Pediatrics, 2018, Vol 64, Issue 4, p304
- ISSN
0142-6338
- Publication type
journal article
- DOI
10.1093/tropej/fmx067