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An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles.
Published in:
Journal of Extracellular Vesicles, 2023, v. 12, n. 2, p. 1, doi. 10.1002/jev2.12304
By:
- Barreiro, Karina;
- Lay, Abigail C.;
- Leparc, German;
- Tran, Van Du T.;
- Rosler, Marcel;
- Dayalan, Lusyan;
- Burdet, Frederic;
- Ibberson, Mark;
- Coward, Richard J. M.;
- Huber, Tobias B.;
- Krämer, Bernhard K.;
- Delic, Denis;
- Holthofer, Harry
Publication type:
Article
Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function.
Published in:
FASEB Bioadvances, 2019, v. 1, n. 8, p. 498, doi. 10.1096/fba.2019-00011
By:
- Hurcombe, Jennifer A.;
- Lay, Abigail C.;
- Ni, Lan;
- Barrington, Alexandra F.;
- Woodgett, Jim R.;
- Quaggin, Susan E.;
- Welsh, Gavin I.;
- Coward, Richard J.
Publication type:
Article
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.
Published in:
Diabetologia, 2021, v. 64, n. 7, p. 1690, doi. 10.1007/s00125-021-05427-1
By:
- Lay, Abigail C.;
- Hale, Lorna J.;
- Stowell-Connolly, Holly;
- Pope, Robert J. P.;
- Nair, Viji;
- Ju, Wenjun;
- Marquez, Eva;
- Rollason, Ruth;
- Hurcombe, Jenny A.;
- Hayes, Bryony;
- Roberts, Timothy;
- Gillam, Lawrence;
- Allington, Jonathan;
- Nelson, Robert G.;
- Kretzler, Matthias;
- Holly, Jeff M. P.;
- Perks, Claire M.;
- McArdle, Craig A.;
- Welsh, Gavin I.;
- Coward, Richard J. M.
Publication type:
Article
Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor.
Published in:
Diabetologia, 2017, v. 60, n. 11, p. 2299, doi. 10.1007/s00125-017-4394-0
By:
- Lay, Abigail;
- Hurcombe, Jenny;
- Betin, Virginie;
- Barrington, Fern;
- Rollason, Ruth;
- Ni, Lan;
- Gillam, Lawrence;
- Pearson, Grace;
- Østergaard, Mette;
- Hamidi, Hellyeh;
- Lennon, Rachel;
- Welsh, Gavin;
- Coward, Richard
Publication type:
Article
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46132-y
By:
- Xu, Xiaoguang;
- Khunsriraksakul, Chachrit;
- Eales, James M.;
- Rubin, Sebastien;
- Scannali, David;
- Saluja, Sushant;
- Talavera, David;
- Markus, Havell;
- Wang, Lida;
- Drzal, Maciej;
- Maan, Akhlaq;
- Lay, Abigail C.;
- Prestes, Priscilla R.;
- Regan, Jeniece;
- Diwadkar, Avantika R.;
- Denniff, Matthew;
- Rempega, Grzegorz;
- Ryszawy, Jakub;
- Król, Robert;
- Dormer, John P.
Publication type:
Article
Podocyte Bioenergetics in the Development of Diabetic Nephropathy: The Role of Mitochondria.
Published in:
Endocrinology, 2022, v. 163, n. 1, p. 1, doi. 10.1210/endocr/bqab234
By:
- Audzeyenka, Irena;
- Bierżyńska, Agnieszka;
- Lay, Abigail C
Publication type:
Article
Does FFAR4 Agonism have Therapeutic Potential in Cardiometabolic Disease?
Published in:
Endocrinology, 2021, v. 162, n. 10, p. 1, doi. 10.1210/endocr/bqab145
By:
- Lay, Abigail C
Publication type:
Article
The Evolving Importance of Insulin Signaling in Podocyte Health and Disease.
Published in:
Frontiers in Endocrinology, 2018, p. N.PAG, doi. 10.3389/fendo.2018.00693
By:
- Lay, Abigail C.;
- Coward, Richard J. M.
Publication type:
Article
Recent advances in our understanding of insulin signalling to the podocyte.
Published in:
Nephrology Dialysis Transplantation, 2014, v. 29, n. 6, p. 1127, doi. 10.1093/ndt/gft471
By:
- Lay, Abigail;
- Coward, Richard J.
Publication type:
Article
Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome.
Published in:
Science Translational Medicine, 2023, v. 15, n. 708, p. 1, doi. 10.1126/scitranslmed.abc8226
By:
- Ding, Wen Y.;
- Kuzmuk, Valeryia;
- Hunter, Sarah;
- Lay, Abigail;
- Hayes, Bryony;
- Beesley, Matthew;
- Rollason, Ruth;
- Hurcombe, Jennifer A.;
- Barrington, Fern;
- Masson, Catrin;
- Cathery, William;
- May, Carl;
- Tuffin, Jack;
- Roberts, Timothy;
- Mollet, Geraldine;
- Chu, Colin J.;
- McIntosh, Jenny;
- Coward, Richard J.;
- Antignac, Corinne;
- Nathwani, Amit
Publication type:
Article

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