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- Title
Manipulating MicroRNAs to Regulate Macrophage Polarization in Gliomas.
- Authors
Anand, Sudarshan; Coussens, Lisa M.
- Abstract
The article discusses the importance of understanding the role played by tumor associated macrophages when using microRNA as a treatment for glioblastoma, which was the subject of the study by Xu and colleagues. Topics discussed include their discovery of miR-143-3p's functional significance in glioblastoma, other studies that focused on the function of miR-142-3p and other possible targets aside from the TGFβ pathway.
- Subjects
GLIOBLASTOMA multiforme treatment; MICRORNA; CANCER treatment; MACROPHAGES; THERAPEUTICS
- Publication
JNCI: Journal of the National Cancer Institute, 2014, Vol 106, Issue 8, p1
- ISSN
0027-8874
- Publication type
Article
- DOI
10.1093/jnci/dju230