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- Title
Profound lymphopenia and bacteraemia.
- Authors
Hawkins, C. A.; Collignon, P.; Adams, D. N.; Bowden, F. J.; Cook, M. C.
- Abstract
Bacteraemia often carries a poor prognosis despite prompt antibiotic therapy and is associated with late morbidity and mortality that is difficult to explain. Here, we describe perisistent B- and T- cell lymphopenia in a cohort of patients with Gram-positive and Gram-negative bacteraemia. This suggests previously unrecognized mechanisms of subversion of immunity by pathogens and might explain the comorbidity of blood stream infection with bacteria.
- Subjects
BACTEREMIA; BACTERIAL diseases; INFECTION; BLOOD diseases; T cells
- Publication
Internal Medicine Journal, 2006, Vol 36, Issue 6, p385
- ISSN
1444-0903
- Publication type
Article
- DOI
10.1111/j.1445-5994.2006.01076.x