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- Title
Reaction of Nitrilimines with Pyruvaldehyde Hydrazones: Synthesis and Antimicrobial Evaluation of Some New 1,2,4-Triazole Derivatives.
- Authors
Dalloul, Hany M.
- Abstract
A new series of 1,3,4,5,5-pentasubstituted-1,2,4-triazoles (4a–j, 6a–j) have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines 2 to pyruvaldehyde (2-oxopropanal) hydrazones having (COPh, COOMe, COOEt, Me/Me, and Me/Ph) groups 3 and 5. Both analytical and spectroscopical data of all the synthesized compounds are in full agreement with the proposed structures. The microbial features of the synthesized compounds were studied by a known method.
- Subjects
NITRILIMINES; PYRUVALDEHYDE; HYDRAZONES; ANTI-infective agents; TRIAZOLE derivatives; CHEMICAL synthesis; CHEMICAL reactions
- Publication
Journal of Chemistry, 2015, Vol 2015, p1
- ISSN
2090-9063
- Publication type
Article
- DOI
10.1155/2015/593738