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- Title
Prediction of Preterm Birth with Serial Measurements of Ultrasound Markers.
- Authors
VICTORIA CAMEN, IOANA; MANOLEA, MARIAMAGDALENA; VRABIE, SIDONIA CATALINA; SANDULESCU, MARIA SIDONIA; SERBANESCU, MIRCEA SEBASTIAN; BOLDEANU, MIHAIL VIRGIL; NOVAC, LILIANA; ISTRATE-OFITERU, ANCA MARIA; DANIELANEAMTU, SIMONA; LORENADIJMARESCU, ANDA
- Abstract
To compare the ability of cervical length (CL), anterior cervical angle (ACA), and cervical consistency index (CCI) to predict premature birth. Methods. This prospective study involved 85 pregnant women who gave birth prematurely and a control group of 31 pregnant women who gave birth at term. The study was performed in the Obstetrics and Gynecology Clinic of the Municipal Clinical Hospital Filanthropia Craiova between January 1, 2019, and January 1, 2022. Cases were examined using transvaginal ultrasonography (TVU) in the second and third trimesters of pregnancy, and cervical length (CL), Anterior Cervical Angle (ACA), and Cervical Consistency Index (CCI) were measured. Results. The mean value from the three measurements at all three parameters was statistically significant with preterm birth (p<0.05). Cervical length <25mm, was highly significant in the prediction of preterm labor with a sensitivity of 99%, specificity of 61%, positive predictive value (PPV) of 78%, negative predictive value (NPV) of 97 %, and a positive likelihood ratio (LR+) of 2.54 and negative likelihood ratio (LR-) of 0.02. CCI also remains, despite low specificity and PPV values, a potential predictive parameter in the prediction of preterm birth, with a sensitivity of 73%, NPV of 92% and a LR+of 1.32 and LR-of 0.6 also correlated with CL, CCI being more difficult to interpret as an independent predictive parameter. Conclusions. CL remains the standard parameter for predicting the preterm birth, but in combination with other parameters, the prediction rate can increase significantly.
- Subjects
PREMATURE labor; THIRD trimester of pregnancy; SECOND trimester of pregnancy; TRANSVAGINAL ultrasonography; PREGNANT women
- Publication
Current Health Sciences Journal, 2022, Vol 48, Issue 2, p162
- ISSN
2067-0656
- Publication type
Article
- DOI
10.12865/CHSJ.48.02.04