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- Title
Hybrid Monoterpenoid Indole Alkaloids Obtained as Artifacts from Rauvolfia tetraphylla.
- Authors
Gao, Yuan; Zhou, Dong-Sheng; Hai, Ping; Li, Yan; Wang, Fei
- Abstract
Five new hybrid monoterpenoid indole alkaloids bearing an unusual 2,2-dimethyl-4-oxopiperidin-6-yl moiety, namely rauvotetraphyllines F-H ( 1, 3, 4), 17- epi-rauvotetraphylline F ( 2) and 21- epi-rauvotetraphylline H ( 5), were isolated from the aerial parts of Rauvolfia tetraphylla. Their structures were established by extensive spectroscopic analysis. The new alkaloids were evaluated for their cytotoxicity in vitro against five human cancer cell lines. Graphical Abstract: [Figure not available: see fulltext.]
- Publication
Natural Products & Bioprospecting, 2015, Vol 5, Issue 5, p247
- ISSN
2192-2209
- Publication type
Article
- DOI
10.1007/s13659-015-0074-2