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- Title
The involvement of CD36 in monocyte activation by antiphospholipid antibodies.
- Authors
Kato, M; Atsumi, T; Oku, K; Amengual, O; Nakagawa, H; Fujieda, Y; Otomo, K; Horita, T; Yasuda, S; Koike, T
- Abstract
The article presents a study which investigates the possible involvement of CD36, a transmembrane glycoprotein, in the thrombosis' pathophysiology in antiphospholipid syndrome (APS) patients. The study made use of the TaqMan polymerase chain reaction (PCR) to investigate rs3765187, a missense mutation associated to CD36 deficiency. The result of the study shows that patients with APS has less frequent minor allele carrier of rs3765187.
- Subjects
ANTIPHOSPHOLIPID syndrome; CD36 antigen; PATHOLOGICAL physiology; POLYMERASE chain reaction; ALLELES; MISSENSE mutation; PATIENTS
- Publication
Lupus, 2013, Vol 22, Issue 8, p761
- ISSN
0961-2033
- Publication type
Article
- DOI
10.1177/0961203313490242