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- Title
Enzooty of non‐Hodgkin's malignant lymphoma of <italic>Papio hamadryas</italic> in Sukhumi monkey colony. Clinical and morphological signs of pre‐lymphoma.
- Authors
Yakovleva, Lelita A.; Lapin, Boris A.; Agumava, Aslan A.
- Abstract
Abstract: Inoculation of hamadryas baboons with blood of leukemia ill people‐induced malignant non‐Hodgkin's lymphoma in experimental animals for a very considerable latency period. At close contact of inoculated baboons with healthy non‐inoculated animals, the lymphoma spread between them. The epidemiological analysis, postmortem examination, histological analysis, tissue culturing, and PCR were used for the diagnostics of lymphoma and pre‐lymphoma, purification, identification of STLV‐1, and HVP viruses. Characteristic clinical and morphological signs designated by us as pre‐lymphoma often precede the lymphoma development. In some cases, pre‐lymphoma does not develop in lymphoma because animals die from various diseases and do not reach the point of the lymphoma development. The horizontal transmission of lymphoma arising with the participation of T‐lymphotropic retrovirus STLV‐1 is shown.
- Subjects
HAMADRYAS baboon; LYMPHOMAS; VACCINATION; EPIDEMIOLOGY; PRIMATOLOGY
- Publication
Journal of Medical Primatology, 2018, Vol 47, Issue 2, p136
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/jmp.12327