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- Title
Management of Nodular Sclerosis Hodgkin's Disease Stage I, II A and B: Evidence for a Beneficial Effect of MOPP on the Relapse Rate.
- Authors
Lauria, Francesco; Baccarani, Michele; Babini, Lucio; Emiliani, Ermanno; Fiacchini, Mauro; Gobbi, Marco; Mazza, Patrizio; Sciascia, Ruggero; Tura, Sante
- Abstract
85 patients with previously untreated Hodgkin's disease with stage I, II A and B nodular sclerosis were treated. 31 of them with stage I and II A were submitted to radiotherapy alone. All are alive, but 9 of them (30%) relapsed. On the contrary, 35 patients with stage I and II A, and 19 with stage I, II and IIE B were submitted to radiotherapy followed by three courses of MOPP. All 54 patients are alive and relapse-free. No severe complication related to chemotherapy was observed. The analysis of results suggests that 3 courses of MOPP can significantly (p < 0.00025) reduce the relapse rate in patients with stage I and II nodular sclerosis, eligible for radiotherapy, without increasing morbidity. Copyright © 1979 S. Karger AG, Basel
- Publication
Acta Haematologica, 1979, Vol 62, Issue 5/6, p262
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000207585