Title

Solitary Fibrous Tumor arising in extremity: A report of two cases with 201-Thallium Scintigraphic and PET findings.

Authors

Fukui, Tomoaki; Kawaguchi, Yoji; Kawamoto, Teruya; Hitora, Toshiaki; Yamamoto, Tetsuji; Akisue, Toshihiro; Kushida, Yoshio; Haba, Reiji

Abstract

We report two cases of solitary fibrous tumor affecting the extremities, with 201-thallium scintigraphic and positron emission tomographic appearance. Preoperative magnetic resonance imaging features in both cases were non-specific. Both patients underwent a wide excision. Histologically, case 1 showed spindle cells growing in "patternless pattern" with malignant findings, as hypercellularity, nuclear pleomorphism and high mitotic activity. Case 2 was also composed of spindle cells, but showed benign histological findings. CD34, bcl-2 and CD99 were positive in both cases, and Ki-67 labeling index was high. In neither case, the preoperative 201-thallium scintigraphic and positron emission tomographic findings were not compatible with the histologic tumor grade. Thus, 201-thallium scintigraphic and positron emission tomographic findings do not precisely predict the histological grade in solitary fibrous tumor and biopsy is necessary.

Subjects

DISEASES of the anatomical extremities; POSITRON emission; POSITRON emission tomography; MAGNETIC resonance imaging; SURGICAL excision; POLYMORPHISM (Crystallography)

Publication

Cancer Therapy, 2008, Vol 6, Issue 2, p1017

ISSN

1543-9135

Publication type

Academic Journal