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- Title
BI-HEX®-GlymaxX® cells enable efficient production of next generation biomolecules with enhanced ADCC activity.
- Authors
Puklowski, Anja; Wenger, Till; Schatz, Simone; Koenitzer, Jennifer; Schaub, Jochen; Enenkel, Barbara; Khetan, Anurag; Kaufmann, Hitto; Tolstrup, Anne B.
- Abstract
The article presents a study which discusses use of BI-HEX-GlymaxX host cell line which help in efficient production of next generation biomolecules with enhanced antibody dependent cellular cytotoxicity (ADCC) activity. Topics discussed include the pharmaceutical firm Boehringer Ingelheim inlicensing the GlymaxX system from ProBioGen for the study, the BI-HEX host cell line transfected with the bacterial RMD enzyme, and presence of RMD confirmed by Western blotting.
- Subjects
BIOMOLECULES; ANTIBODY-dependent cell cytotoxicity; BOEHRINGER Ingelheim GmbH; PROBIOGEN AG; CELL lines; WESTERN immunoblotting
- Publication
BMC Proceedings, 2013, p1
- ISSN
1753-6561
- Publication type
Article
- DOI
10.1186/1753-6561-7-S6-P63