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- Title
La importancia de la comorbilidad en el fracaso renal agudo valorado por los nefrólogos.
- Authors
Ortiz Libero, M.; Mon Mon, C.; Herrero Berrón, J. C.; Lentisco Ramírez, C.; Gracia Iguacel, C.; Oliet Pala, A.; Vigil Medina, A. l.; Ortega Marcos, O.; Gallar Ruiz, P.; Rodriguez Villareal, I.; Sánchez Sánchez, M.
- Abstract
Aims: To study the features of acute renal failure (ARF) in our hospital and to determine prognosis and mortality associated factors. Methods: This is a retrospective study analyzing the ARF episodes observed in our center during a two years period (2005-2007). ARF was considered when a sudden rise in serum creatinine concentration was more than 0, 5 mg/dl in patients with normal renal function and more than 1 mg/dl in patients with previous mild to moderate chronic renal failure. We analyzed epidemiologic, clinical, laboratories results, therapeutics and prognosis factors. Results: Two hundred and one patients were evaluated (62, 7% males; Age= 67,35 ± 16,38 years (63,68% >65 años); Comorbility Index of Charlson was 3,49 ± 2,43). 115 ARF episodes occurred in patients with previous renal failure. ARF was pre-renal in 52, 7%, renal in 34,8% and post-renal in 8,5%. 35,8% of ARF patients had oliguria or anuria. The mean duration of ARF/hospitalization was 22,47 days (22,47 ± 21,83). The percentage of resolved ARF was 70, 1%. Mortality was 30, 8%. The univariate analysis showed that comorbility Index of Charlson, oliguria, low serum albumin, low cholesterol and anemia were significantly associated with mortality (p <0,05). However, only Charlson Index, oliguria and low serum cholesterol were independent predictors of mortality in multivariate analysis. Mortality predictive model was carried out. Conclusion: Highest basal comorbility of patients, oliguria and malnutritioninflamation dates are independent predictors of mortality in patients with acute renal failure.
- Subjects
ACUTE kidney failure; COMORBIDITY; KIDNEY diseases; MORTALITY; OLIGURIA; ANEMIA; MULTIVARIATE analysis; RETROSPECTIVE studies; PROGNOSIS
- Publication
Nefrologia, 2009, Vol 29, Issue 5, p430
- ISSN
0211-6995
- Publication type
Article