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- Title
Demonstration of the metaphylactic use of gamithromycin against bacterial pathogens associated with bovine respiratory disease in a multicentre farm trial.
- Authors
Baggott, D.; Casartelli, A.; Fraisse, F.; Manavella, C.; Marteau, R.; Rehbein, S.; Wiedemann, M.; Yoon, S.
- Abstract
On five commercial cattle rearing sites across Europe, a total of 802 young cattle at high risk of developing bovine respiratory disease (BRD) associated with the bacterial pathogens or and/or were enrolled into a multicentre, controlled field trial. Half were treated with a single dose of gamithromycin at 6 mg/kg bodyweight by subcutaneous injection and half received an injection of a saline placebo as the control. All animals were observed daily for 14 days for signs of BRD as defined by set criteria. The proportion of metaphylactic preventive treatment successes, defined as animals surviving to day 14 without signs of BRD, in the gamithromycin-treated group (86 per cent) was significantly (P=0.0012) higher than in the saline-treated controls (61 per cent). Morbidity among the treated animals was reduced by 64 per cent compared with the controls.
- Publication
Veterinary Record: Journal of the British Veterinary Association, 2011, Vol 168, Issue 9, p241
- ISSN
0042-4900
- Publication type
Article
- DOI
10.1136/vr.c6776