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- Title
Skin Ferrochelatase and Photosensitivity in Mice and Man.
- Authors
Wahlin, Staffan; Harper, Pauline
- Abstract
The article examines a study conducted by Pawliuk and colleagues concerning the contribution of erythroid, dermal, and hepatic ferrochelatase (FECH) to human and mice. It stresses that the transplantation of normal skin to erythropoietic protoporphyria (EPP) mice suggested that restoration of dermal FECH activity could prevent dermal photosensitivity. Moreover, it is obvious that FECH could also prevent dermal photosensitivity in human EPP.
- Subjects
SKIN disease treatment; TRANSDERMAL medication; ERYTHROCYTE membranes; PHOTOSENSITIVITY disorders; MICE
- Publication
Journal of Investigative Dermatology, 2010, Vol 130, Issue 2, p631
- ISSN
0022-202X
- Publication type
Article
- DOI
10.1038/jid.2009.246