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- Title
Identification of Pro-Differentiation Patterns by Gene Expression Analysis following Pioglitazone Treatment in a Primary Laryngeal Tumor Cell Line.
- Authors
Handley, Nathan R.; Gaffney, Patrick M.; Taylor, Randall S.; Wuertz, Beverly R.; Ondrey, Frank G.
- Abstract
The article presents a clinical study which identifies a pro-differentiation patterns through gene expression analysis after using pioglitazone treatment in a primary laryngeal tumor cell line. It implies that not all genes differentially expressed between normal cells and tumor cells are modulated by pioglitazone. It adds that ingenuity pathway analysis may prove useful for visualizing gene interaction pathways.
- Subjects
LARYNGEAL cancer treatment; GENE expression; CELL lines; CANCER cells; CELLULAR pathology; GENETIC regulation
- Publication
Laryngoscope, 2011, Vol 121, Issue S5, pS281
- ISSN
0023-852X
- Publication type
Article
- DOI
10.1002/lary.22237