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- Title
Putting the Pieces Together: Necrolytic Migratory Erythema and the Glucagonoma Syndrome.
- Authors
Halvorson, Stephanie; Gilbert, Erin; Hopkins, R.; Liu, Helen; Lopez, Charles; Chu, Michael; Martin, Marie; Sheppard, Brett
- Abstract
Glucagonomas are slow-growing, rare pancreatic neuroendocrine tumors. They may present with paraneoplastic phenomena known together as the 'glucagonoma syndrome.' A hallmark sign of this syndrome is a rash known as necrolytic migratory erythema (NME). In this paper, the authors describe a patient with NME and other features of the glucagonoma syndrome. The diagnosis of this rare tumor requires an elevated serum glucagon level and imaging confirming a pancreatic tumor. Surgical and medical treatment options are reviewed. When detected early, a glucagonoma is surgically curable. It is therefore imperative that clinicians recognize the glucagonoma syndrome in order to make an accurate diagnosis and refer for treatment.
- Subjects
ERYTHEMA; GLUCAGONOMA; NEUROENDOCRINE tumors; PANCREATIC tumors; GLUCAGON; DIAGNOSIS; PATIENTS
- Publication
JGIM: Journal of General Internal Medicine, 2013, Vol 28, Issue 11, p1525
- ISSN
0884-8734
- Publication type
Article
- DOI
10.1007/s11606-013-2490-5