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- Title
Bronchodilation test in patients with allergic rhinitis.
- Authors
Ciprandi, G.; Signori, A.; Tosca, M. A.; Cirillo, I.
- Abstract
Background: Allergic rhinitis (AR) may be considered a risk factor for the onset of asthma. Recently, it has been reported that forced expiratory flow between 25% and 75% of vital capacity (FEF25-75) may predict a positive response to bronchodilation test in asthmatic children. The aim of this study was to evaluate a large group of adult AR patients to investigate the frequency of response to bronchodilation test and FEF25-75 values. Methods: One thousand four hundred and sixty-nine consecutive patients suffering from persistent AR were evaluated. Clinical examination, spirometry, and bronchodilation test were performed in all patients. Results: In this study, 62.9% of patients had reversibility to bronchodilation test and 17.8% had impaired FEF25-75 values (⩽65% of predicted). Impaired FEF25-75 values associated with longer rhinitis duration may predict reversibility to bronchodilation test (OR = 11.3; P < 0.001). In addition, a FEF25-75 cutoff value ⩽71% of predicted may already discriminate patients with reversibility. Conclusions: This study highlights that about two-thirds of patients with persistent AR may be considered at risk of becoming asthmatic. This finding should be adequately considered as a precocious spirometry may allow the early detection of patients prone to develop asthma and consequently to treat them.
- Subjects
ALLERGIC rhinitis; ASTHMA risk factors; BRONCHODILATOR agents; ASTHMA in children; NOSE diseases
- Publication
Allergy, 2011, Vol 66, Issue 5, p694
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/j.1398-9995.2011.02544.x