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- Title
Overexpression of c-myc in the liver prevents obesity and insulin resistance.
- Authors
Riu, Efren; Ferre, Tura; Hidalgo, Antonio; Mas, Alex; Franckhauser, Sylvie; Otaegui, Pedro; Bosch, Fatima
- Abstract
Examines whether hepatic overexpression of c-myc counteracted obesity and insulin resistance are induced by a high-fat diet. Factor that blocks glucogenesis; Effect of c-myc overexpression on the expression and activity of key genes involved in the control of hepatic glycolysis; Diet of transgenic mice overexpressing c-myc.
- Subjects
LIVER cells; OBESITY; BODY weight; INSULIN resistance; DRUG resistance; DIABETES complications; GLYCOLYSIS; SUGAR in the body
- Publication
FASEB Journal, 2003, Vol 17, Issue 12, p1715
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.02-1163fje