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- Title
Recent advances to Neuroprotection: repurposing drugs against neuroinflammatory disorders.
- Authors
Bilal, Wishah; Khawar, Muhammad Babar; Afzal, Ali; Naseer, Arshia; Hamid, Syeda Eisha; Shahzaman, Sara; Qamar, Fareeha
- Abstract
Cell death is a natural mechanism for biological clearance for the maintenance of homeostasis in a dynamic microenvironment of the central nervous system. Stress and various factors can lead to imbalance between cellular genesis and cell death leading to dysfunctionality and a number of neuropathological disorders. Drug repurposing can help bypass development time and cost. A complete understanding of drug actions and neuroinflammatory pathways can lead to effective control of neurodegenerative disorders. This review covers recent advances in various neuroinflammatory pathways understanding, biomarkers, and drug repurposing for neuroprotection.
- Subjects
DRUG repositioning; NEUROLOGICAL disorders; CENTRAL nervous system; CELL death; NEURODEGENERATION; HOMEOSTASIS
- Publication
Molecular Biology Reports, 2023, Vol 50, Issue 7, p6241
- ISSN
0301-4851
- Publication type
Article
- DOI
10.1007/s11033-023-08490-6