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- Title
Use of Kidneys from Anencephalic Donors to Offset Organ Shortage.
- Authors
Nghiem, Dai D.
- Abstract
Background: It is well recognized that patient survival and quality of life are superior with renal transplantation than with dialysis. Organ availability is far outweighed by the large number of wait-listed patients. Additional stratagems are sought to expand the donor pool, and kidneys from anencephalic infants can be considered a source of organs, until now unexplored. We plan to assess the feasibility of using the kidneys from anencephalic infants for transplantation. Material and Methods: Information about anencephaly, the characteristics of the infant kidneys, the ethical, social and medico-legal aspects raised by the use of these kidneys, their procurement and their transplantation are reviewed. Conclusions: En bloc kidney transplants from infants can provide long-term normal renal function after an accelerated catch up growth. They are not subjected to hyperfiltration since they have a full complement of nephrons. They can be transplanted using the techniques currently available.
- Subjects
KIDNEY transplantation; QUALITY of life; LONG-term health care; INFANTS; ORGAN donation
- Publication
Uro, 2023, Vol 3, Issue 1, p10
- ISSN
2673-4397
- Publication type
Article
- DOI
10.3390/uro3010002