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- Title
Aging Combined with High Waist-to-Hip Ratio Is Associated with a Higher Risk of Gastro-Esophageal Reflux Disease.
- Authors
Yu, Lo-Yip; Lin, Ying-Chun; Kuo, Yang-Che; Ko, Hung-Ju; Chen, Ming-Jen; Wang, Horng-Yuan; Shih, Shou-Chuan; Liu, Chuan-Chuan; Hu, Kuang-Chun
- Abstract
Background and Objective: To assess whether the combination of high waist-to-hip ratio (WHR) and elderly age is associated with higher risk of GERD. Material and Methods: A total of 16,996 subjects aged ≥20 years who received esophagogastroduodenoscopy (EGD) between January 2010 and December 2019. We evaluated the risk of GERD in different age groups and WHR groups in unadjusted analysis and multivariate logistic regression models for predictors of GERD. Results: There was a trend towards more participants with both age ≥65 years and WHR ≥ 1 (n = 129) (n = 66, 51%) than participants with age < 65 and WHR < 0.9 (n = 10,422) (n = 2814, 27%) presenting with GERD. Participants who had both age ≥ 65 years and high WHR ≥ 1 had the highest risk of any type of GERD (adjusted OR, 2.07; 95% CI, 1.44–2.96, p value < 0.05) based on multivariate logistic regression analysis. Conclusions: The combination of having a high WHR and being elderly was associated with a higher risk of GERD, and preventing central obesity in the elderly population reduced the risk of GERD and the requirement for medical resources.
- Subjects
WAIST-hip ratio; GASTROESOPHAGEAL reflux; OLDER people; LOGISTIC regression analysis; AGE groups; AGING
- Publication
Journal of Clinical Medicine, 2022, Vol 11, Issue 17, p5224
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm11175224