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- Title
Phylogeny of SINE-R Retroposons in Asian Apes.
- Authors
Heui-Soo Kim; Takenaka, Osamu
- Abstract
The SINE-R retroposon family was derived from the long terminal repeats (LTRs) of human endogenous retrovirus K (HERV-K) that had been active during the hominoid evolution. The retroposons and HERV-K LTR elements have potential relevance to structural change and genetic variation of the hominoid genome. In our previous study, we found that the SINE-R retroposons were hominoid specific. Here we identified seventeen new SINE-R retroposons (14 from orangutan and 3 from gibbon) from Asian apes and phylogenetically analysed them in comparison with those of the humans and African great apes. None of the retroposons from Asian apes were closely related to SINE-R.C2 that is human specific, and originally identified in the gene for the C2 component of complement, whereas some retroposons (Ch-M10, Ch-M16, Gor-M, Gor-F1, Gor-M6, and Gor-F9) from African great apes showed very close relationship with that of the SINE-R.C2 retroposon. The phylogenetic tree based on the SINE-R retroposons revealed wide overlap of the retroposons across species, suggesting that the SINE-R retroposons have been evolved parallel pattern in the course of hominoid evolution.
- Subjects
RETROVIRUSES; HUMAN evolution; GENETICS; GENOMES; APES; PHYLOGENY
- Publication
Molecules & Cells (Springer Nature), 2001, Vol 12, Issue 2, p262
- ISSN
1016-8478
- Publication type
Article
- DOI
10.1016/s1016-8478(23)17094-4